Long-Term Survival and Biomarker Analysis Evaluating Neoadjuvant Plus Adjuvant Relatlimab (anti-LAG3) and Nivolumab (anti-PD1) in Patients With Resectable Melanoma Our study included a broad cohort of ...

The tool enables researchers to pinpoint which proteins work together to drive this essential process. The importance of this is paramount, as the failure of mitosis leads to defects such as fertility ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Before new drugs can be tested in animal experiments and later in clinical trials, they must undergo a large number of laboratory tests. This involves the use of so-called cell lines, i.e. human or ...

Using human embryonic stem cells, researchers have created a model that allows them to track cellular behavior during the earliest stages of human development in real-time. The model reveals, for the ...

How do we grow from a single fertilized egg into a fully grown person with trillions of cells? Our cells divide, of course! And it's no mean feat. Each time a cell divides, it must duplicate our 23 ...

Cell therapy is a promising alternative to tissue and organ transplantation for diseases that are caused by death or poor functioning of cells. Considering the ethical discussions surrounding human ...

PEM fuel cells have good efficiency and low operating temperature and could play an important role in power generation in the future. They are currently the leading technology for automotive ...

Effectiveness of Endoscopic Screening on Esophageal Cancer Incidence and Mortality: A 9-Year Report of the Endoscopic Screening for Esophageal Cancer in China (ESECC) Randomized Trial This is an ...

Chronic pain is the most common complication affecting adults with sickle cell disease (SCD). 1 Pain profoundly affects people’s quality of life, functional ability, and health care utilization.