To simulate trans-ethnic meta-analysis, we performed a GWAS meta-analysis for a given iteration across all ancestral populations using the inverse-variance method with the assumption of a fixed-effect ...

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...

A history of the selection of the widely used significance level leaves much to be desired. Statisticians and non-statisticians daily select the level of statistical significance to be used for ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

A small p-value often means the observed data effect is statistically significant. Set a significance level to compare with the p-value to validate investment hypotheses. Utilizing p-values in Excel ...

A recent study that questioned the healthfulness of eggs raised a perpetual question: Why do studies, as has been the case with health research involving eggs, so often flip-flop from one answer to ...