DSBs can be repaired using several different mechanisms. Both ends can be simply rejoined with little or no further processing (nonhomologous end joining, or NHEJ) or can be repaired using homologous ...
One of the hallmarks of DNA damage is the rapid spreading of phosphorylated histone H2A (γ-H2AX) around a DNA double-strand break (DSB). In the budding yeast Saccharomyces cerevisiae, nearly all H2A ...
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