Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the earliest stages of embryonic development. These mosaic mutations often go ...

Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are medical conditions characterized by the progressive degradation ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

Previously overlooked regions at the start of human genes have been shown to accumulate mutations far more often than would ...

Scientists at Cincinnati Children's have taken a key early step in understanding why some people born with the rare disease Adams-Oliver syndrome (AOS) experience potentially fatal disruptions in ...

Lung cancer remains the most frequently diagnosed malignancy and the leading cause of cancer tumour-related mortality ...

This study presents a large, systematically curated catalog of non-canonical open reading frames (ncORFs) in human and mouse by reanalyzing nearly 400 Ribo-seq datasets using a standardized pipeline; ...

For years, TRISH has supported research projects and studies that aim to solve the challenges of human exploration in space. To understand how to solve those challenges, we first must know the risks ...

Bacteria that multiply on surfaces are a major headache in health care when they gain a foothold on, for example, implants or ...

Globally, metabolic dysfunction-associated steatotic liver disease (MASLD) is now the most common chronic liver disease, affecting up to one in three people in the general population, with an ...

Sharpen your Mains answer-writing skills with GS-3 questions by following the thought process. Do not miss points to ponder ...