Many neurodegenerative diseases are characterized by impairment of protein quality control mechanisms in neuronal cells. Ineffective clearance of misfolded proteins by the proteasome, autophagy ...
(1) Plant spatial patterns and their relationship with sheep grazing and the underlying soil patterns were examined in a dune grassland at Newborough Warren, Anglesey, Wales. (2) In the absence of ...
Cell-directed changes in the ligand-binding affinity ('activation') of integrins regulate cell adhesion and migration, extracellular matrix assembly and mechanotransduction. The final intracellular ...